Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment

BACKGROUND: Trypanosoma cruzi is the etiological agent of Chagas' disease, an endemic infection that causes thousands of deaths every year in Latin America. Therapeutic options remain inefficient, demanding the search for new drugs and/or new molecular targets. Such efforts can focus on protein...

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Detalles Bibliográficos
Autores principales: Capriles, Priscila VSZ, Guimarães, Ana CR, Otto, Thomas D, Miranda, Antonio B, Dardenne, Laurent E, Degrave, Wim M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091751/
https://www.ncbi.nlm.nih.gov/pubmed/21034488
http://dx.doi.org/10.1186/1471-2164-11-610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091751/
https://www.ncbi.nlm.nih.gov/pubmed/21034488
http://dx.doi.org/10.1186/1471-2164-11-610

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