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Low-Dose Adrenaline, Promethazine, and Hydrocortisone in the Prevention of Acute Adverse Reactions to Antivenom following Snakebite: A Randomised, Double-Blind, Placebo-Controlled Trial

BACKGROUND: Envenoming from snakebites is most effectively treated by antivenom. However, the antivenom available in South Asian countries commonly causes acute allergic reactions, anaphylactic reactions being particularly serious. We investigated whether adrenaline, promethazine, and hydrocortisone...

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Detalles Bibliográficos
Autores principales: de Silva, H. Asita, Pathmeswaran, Arunasalam, Ranasinha, Channa D., Jayamanne, Shaluka, Samarakoon, Senarath B., Hittharage, Ariyasena, Kalupahana, Ranjith, Ratnatilaka, G. Asoka, Uluwatthage, Wimalasiri, Aronson, Jeffrey K., Armitage, Jane M., Lalloo, David G., de Silva, H. Janaka
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091849/
https://www.ncbi.nlm.nih.gov/pubmed/21572992
http://dx.doi.org/10.1371/journal.pmed.1000435