DNA Methyltransferase Controls Stem Cell Aging by Regulating BMI1 and EZH2 through MicroRNAs

Epigenetic regulation of gene expression is well known mechanism that regulates cellular senescence of cancer cells. Here we show that inhibition of DNA methyltransferases (DNMTs) with 5-azacytidine (5-AzaC) or with specific small interfering RNA (siRNA) against DNMT1 and 3b induced the cellular sen...

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Detalles Bibliográficos
Autores principales: So, Ah-Young, Jung, Ji-Won, Lee, Seunghee, Kim, Hyung-Sik, Kang, Kyung-Sun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091856/
https://www.ncbi.nlm.nih.gov/pubmed/21572997
http://dx.doi.org/10.1371/journal.pone.0019503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091856/
https://www.ncbi.nlm.nih.gov/pubmed/21572997
http://dx.doi.org/10.1371/journal.pone.0019503

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