A Non-Specific Effect Associated with Conditional Transgene Expression Based on Cre-loxP Strategy in Mice

Transgenes flanked by loxP sites have been widely used to generate transgenic mice where the transgene expression can be controlled spatially and temporally by Cre recombinase. Data from this approach has led to important conclusions in cancer, neurodevelopment and neurodegeneration. Using this appr...

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Detalles Bibliográficos
Autores principales: Qiu, Linghua, Rivera-Pérez, Jaime A., Xu, Zuoshang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091857/
https://www.ncbi.nlm.nih.gov/pubmed/21572998
http://dx.doi.org/10.1371/journal.pone.0018778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091857/
https://www.ncbi.nlm.nih.gov/pubmed/21572998
http://dx.doi.org/10.1371/journal.pone.0018778

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