Investigating the Role of T-Cell Avidity and Killing Efficacy in Relation to Type 1 Diabetes Prediction

During the progression of the clinical onset of Type 1 Diabetes (T1D), high-risk individuals exhibit multiple islet autoantibodies and high-avidity T cells which progressively destroy beta cells causing overt T1D. In particular, novel autoantibodies, such as those against IA-2 epitopes (aa1-577), ha...

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Detalles Bibliográficos
Autores principales: Khadra, Anmar, Pietropaolo, Massimo, Nepom, Gerald T., Sherman, Arthur
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091860/
https://www.ncbi.nlm.nih.gov/pubmed/21573001
http://dx.doi.org/10.1371/journal.pone.0014796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091860/
https://www.ncbi.nlm.nih.gov/pubmed/21573001
http://dx.doi.org/10.1371/journal.pone.0014796

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