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Insulin Production and Signaling in Renal Tubules of Drosophila Is under Control of Tachykinin-Related Peptide and Regulates Stress Resistance

The insulin-signaling pathway is evolutionarily conserved in animals and regulates growth, reproduction, metabolic homeostasis, stress resistance and life span. In Drosophila seven insulin-like peptides (DILP1-7) are known, some of which are produced in the brain, others in fat body or intestine. He...

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Detalles Bibliográficos
Autores principales: Söderberg, Jeannette A. E., Birse, Ryan T., Nässel, Dick R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091884/
https://www.ncbi.nlm.nih.gov/pubmed/21572965
http://dx.doi.org/10.1371/journal.pone.0019866