The Ras/MAPK Pathway Is Required for Generation of iNKT Cells

iNKT cells derive from CD4(+)CD8(+) DP thymocytes, and are selected by thymocyte-thymocyte interactions through signals from their invariant Vα14-Jα18 TCR and from the costimulatory molecules SLAMF1 and SLAMF6. Genetic studies have demonstrated the contribution of different signaling pathways to thi...

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Detalles Bibliográficos
Autores principales: Hu, Taishan, Gimferrer, Idoia, Simmons, Amie, Wiest, David, Alberola-Ila, José
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091886/
https://www.ncbi.nlm.nih.gov/pubmed/21572967
http://dx.doi.org/10.1371/journal.pone.0019890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091886/
https://www.ncbi.nlm.nih.gov/pubmed/21572967
http://dx.doi.org/10.1371/journal.pone.0019890

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