No compelling evidence that sibutramine prolongs life in rodents despite providing a dose-dependent reduction in body weight

OBJECTIVE: The health and longevity effects of body weight reduction resulting from exercise and caloric restriction in rodents are well known, but less is known about whether similar effects occur with weight reduction from the use of a pharmaceutical agent such as sibutramine, a serotonin-norepine...

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Detalles Bibliográficos
Autores principales: Smith, Daniel L., Robertson, Henry, Desmond, Renee, Nagy, Tim R., Allison, David B.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091992/
https://www.ncbi.nlm.nih.gov/pubmed/21079617
http://dx.doi.org/10.1038/ijo.2010.247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091992/
https://www.ncbi.nlm.nih.gov/pubmed/21079617
http://dx.doi.org/10.1038/ijo.2010.247

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