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No compelling evidence that sibutramine prolongs life in rodents despite providing a dose-dependent reduction in body weight
OBJECTIVE: The health and longevity effects of body weight reduction resulting from exercise and caloric restriction in rodents are well known, but less is known about whether similar effects occur with weight reduction from the use of a pharmaceutical agent such as sibutramine, a serotonin-norepine...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091992/ https://www.ncbi.nlm.nih.gov/pubmed/21079617 http://dx.doi.org/10.1038/ijo.2010.247 |