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Production of Active Nonglycosylated Recombinant B-Chain of Type-2 Ribosome-Inactivating Protein from Viscum articulatum and Its Biological Effects on Peripheral Blood Mononuclear Cells

Type-2 ribosome-inactivating proteins, composed of a toxic A-chain and lectin-like B-chain, display various biological functions, including cytotoxicity and immunomodulation. We here cloned the lectin-like B-chain encoding fragment of a newly identified type-2 RIP gene, articulatin gene, from Viscum...

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Detalles Bibliográficos
Autores principales: Lu, Tzu-Li, Chuang, Jing-Yuan, Yang, Jai-Sing, Chiu, Shau-Ting, Hsiao, Nai-Wan, Wu, Mei-Chen, Wu, Shih-Hsiung, Hsu, Ching-Hsiang
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092231/
https://www.ncbi.nlm.nih.gov/pubmed/21584270
http://dx.doi.org/10.1155/2011/283747