Platelet-derived serotonin links vascular disease and tissue fibrosis

Vascular damage and platelet activation are associated with tissue remodeling in diseases such as systemic sclerosis, but the molecular mechanisms underlying this association have not been identified. In this study, we show that serotonin (5-hydroxytryptamine [5-HT]) stored in platelets strongly ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Dees, Clara, Akhmetshina, Alfiya, Zerr, Pawel, Reich, Nicole, Palumbo, Katrin, Horn, Angelika, Jüngel, Astrid, Beyer, Christian, Krönke, Gerhard, Zwerina, Jochen, Reiter, Rudolf, Alenina, Natalia, Maroteaux, Luc, Gay, Steffen, Schett, Georg, Distler, Oliver, Distler, Jörg H.W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092343/
https://www.ncbi.nlm.nih.gov/pubmed/21518801
http://dx.doi.org/10.1084/jem.20101629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092343/
https://www.ncbi.nlm.nih.gov/pubmed/21518801
http://dx.doi.org/10.1084/jem.20101629

Ejemplares similares