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MHCII glycosylation modulates Bacteroides fragilis carbohydrate antigen presentation

N-linked glycans are thought to protect class II major histocompatibility complex (MHC) molecules (MHCII) from proteolytic cleavage and assist in arranging proteins within the immune synapse, but were not thought to directly participate in antigen presentation. Here, we report that antigen-presentin...

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Detalles Bibliográficos
Autores principales: Ryan, Sean O., Bonomo, Jason A., Zhao, Fan, Cobb, Brian A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092352/
https://www.ncbi.nlm.nih.gov/pubmed/21502329
http://dx.doi.org/10.1084/jem.20100508