Cargando…
The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns
The T-box transcription factor T-bet is important for the differentiation of naive CD4(+) T helper cells (Th cells) into the Th1 phenotype. Much is known about T-bet’s role as a transcriptional activator, but less is known about the mechanisms by which T-bet functionally represses alternative Th cel...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092354/ https://www.ncbi.nlm.nih.gov/pubmed/21518797 http://dx.doi.org/10.1084/jem.20102144 |