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Enzyme Mechanism and Slow-Onset Inhibition of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase by an Inorganic Complex

Malaria continues to be a major cause of children's morbidity and mortality worldwide, causing nearly one million deaths annually. The human malaria parasite, Plasmodium falciparum, synthesizes fatty acids employing the Type II fatty acid biosynthesis system (FAS II), unlike humans that rely on...

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Detalles Bibliográficos
Autores principales: de Medeiros, Patrícia Soares de Maria, Ducati, Rodrigo Gay, Basso, Luiz Augusto, Santos, Diógenes Santiago, da Silva, Luiz Hildebrando Pereira
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092583/
https://www.ncbi.nlm.nih.gov/pubmed/21603269
http://dx.doi.org/10.4061/2011/642758