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Enzyme Mechanism and Slow-Onset Inhibition of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase by an Inorganic Complex
Malaria continues to be a major cause of children's morbidity and mortality worldwide, causing nearly one million deaths annually. The human malaria parasite, Plasmodium falciparum, synthesizes fatty acids employing the Type II fatty acid biosynthesis system (FAS II), unlike humans that rely on...
Autores principales: | de Medeiros, Patrícia Soares de Maria, Ducati, Rodrigo Gay, Basso, Luiz Augusto, Santos, Diógenes Santiago, da Silva, Luiz Hildebrando Pereira |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092583/ https://www.ncbi.nlm.nih.gov/pubmed/21603269 http://dx.doi.org/10.4061/2011/642758 |
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