The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses

Adenoviruses are the most commonly used vectors for gene therapy. Despite the promising safety profile demonstrated in clinical trials, the efficacy of using adenoviruses for gene therapy is poor. A major hurdle to adenoviral-mediated gene therapy is the innate immune system. Cell-mediated recogniti...

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Detalles Bibliográficos
Autores principales: Thaci, Bart, Ulasov, Ilya V., Wainwright, Derek A., Lesniak, Maciej S.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092742/
https://www.ncbi.nlm.nih.gov/pubmed/21399236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092742/
https://www.ncbi.nlm.nih.gov/pubmed/21399236

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