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Degradation of the Disease-Associated Prion Protein by a Serine Protease from Lichens

The disease-associated prion protein (PrP(TSE)), the probable etiological agent of the transmissible spongiform encephalopathies (TSEs), is resistant to degradation and can persist in the environment. Lichens, mutualistic symbioses containing fungi, algae, bacteria and occasionally cyanobacteria, ar...

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Detalles Bibliográficos
Autores principales: Johnson, Christopher J., Bennett, James P., Biro, Steven M., Duque-Velasquez, Juan Camilo, Rodriguez, Cynthia M., Bessen, Richard A., Rocke, Tonie E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092769/
https://www.ncbi.nlm.nih.gov/pubmed/21589935
http://dx.doi.org/10.1371/journal.pone.0019836