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Somatostatin Inhibits Cell Migration and Reduces Cell Counts of Human Keratinocytes and Delays Epidermal Wound Healing in an Ex Vivo Wound Model

The peptide hormone somatostatin (SST) and its five G protein-coupled receptors (SSTR1-5) were described to be present in the skin, but their cutaneous function(s) and skin-specific signalling mechanisms are widely unknown. By using receptor specific agonists we show here that the SSTRs expressed in...

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Detalles Bibliográficos
Autores principales: Vockel, Matthias, Pollok, Simone, Breitenbach, Ute, Ridderbusch, Ina, Kreienkamp, Hans-Jürgen, Brandner, Johanna M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092774/
https://www.ncbi.nlm.nih.gov/pubmed/21589940
http://dx.doi.org/10.1371/journal.pone.0019740