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Somatostatin Inhibits Cell Migration and Reduces Cell Counts of Human Keratinocytes and Delays Epidermal Wound Healing in an Ex Vivo Wound Model
The peptide hormone somatostatin (SST) and its five G protein-coupled receptors (SSTR1-5) were described to be present in the skin, but their cutaneous function(s) and skin-specific signalling mechanisms are widely unknown. By using receptor specific agonists we show here that the SSTRs expressed in...
Autores principales: | Vockel, Matthias, Pollok, Simone, Breitenbach, Ute, Ridderbusch, Ina, Kreienkamp, Hans-Jürgen, Brandner, Johanna M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092774/ https://www.ncbi.nlm.nih.gov/pubmed/21589940 http://dx.doi.org/10.1371/journal.pone.0019740 |
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