Cargando…

The neurotransmitter serotonin interrupts α-synuclein amyloid maturation

Indolic derivatives can affect fibril growth of amyloid forming proteins. The neurotransmitter serotonin (5-HT) is of particular interest, as it is an endogenous molecule with a possible link to neuropsychiatric symptoms of Parkinson disease. A key pathomolecular mechanism of Parkinson disease is th...

Descripción completa

Detalles Bibliográficos
Autores principales: Falsone, S. Fabio, Leitinger, Gerd, Karner, Anita, Kungl, Andreas J., Kosol, Simone, Cappai, Roberto, Zangger, Klaus
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092864/
https://www.ncbi.nlm.nih.gov/pubmed/21376144
http://dx.doi.org/10.1016/j.bbapap.2011.02.008