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The neurotransmitter serotonin interrupts α-synuclein amyloid maturation

Indolic derivatives can affect fibril growth of amyloid forming proteins. The neurotransmitter serotonin (5-HT) is of particular interest, as it is an endogenous molecule with a possible link to neuropsychiatric symptoms of Parkinson disease. A key pathomolecular mechanism of Parkinson disease is th...

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Detalles Bibliográficos
Autores principales:	Falsone, S. Fabio, Leitinger, Gerd, Karner, Anita, Kungl, Andreas J., Kosol, Simone, Cappai, Roberto, Zangger, Klaus
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier Pub. Co 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092864/ https://www.ncbi.nlm.nih.gov/pubmed/21376144 http://dx.doi.org/10.1016/j.bbapap.2011.02.008

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