Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis

For the improved production of vaccines and therapeutic proteins, a detailed understanding of the metabolic dynamics during batch or fed-batch production is requested. To study the new human cell line AGE1.HN, a flexible metabolic flux analysis method was developed that is considering dynamic change...

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Detalles Bibliográficos
Autores principales: Niklas, Jens, Schräder, Eva, Sandig, Volker, Noll, Thomas, Heinzle, Elmar
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092918/
https://www.ncbi.nlm.nih.gov/pubmed/21188421
http://dx.doi.org/10.1007/s00449-010-0502-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092918/
https://www.ncbi.nlm.nih.gov/pubmed/21188421
http://dx.doi.org/10.1007/s00449-010-0502-y

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