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Synthesis of 1-Substituted Carbazolyl-1,2,3,4-tetrahydro- and Carbazolyl-3,4-dihydro-β-carboline Analogs as Potential Antitumor Agents

A series of 1-substituted carbazolyl-1,2,3,4-tetrahydro- and carbazolyl-3,4-dihydro-β-carboline analogs have been synthesized and evaluated for antitumor activity against human tumor cells including KB, DLD, NCI-H661, Hepa, and HepG2/A2 cell lines. Among these, compounds 2, 6, 7, and 9 exhibited the...

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Detalles Bibliográficos
Autores principales: Shen, Ya-Ching, Chang, Yao-To, Lin, Chun-Ling, Liaw, Chia-Ching, Kuo, Yao Haur, Tu, Lan-Chun, Yeh, Sheau Farn, Chern, Ji-Wang
Formato: Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093256/
https://www.ncbi.nlm.nih.gov/pubmed/21566798
http://dx.doi.org/10.3390/md9020256