Cytosolic aggregates perturb the degradation of nontranslocated secretory and membrane proteins

A wide range of diseases are associated with the accumulation of cytosolic protein aggregates. The effects of these aggregates on various aspects of normal cellular protein homeostasis remain to be determined. Here we find that cytosolic aggregates, without necessarily disrupting proteasome function...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Oishee, Rane, Neena S., Hegde, Ramanujan S.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093316/
https://www.ncbi.nlm.nih.gov/pubmed/21411629
http://dx.doi.org/10.1091/mbc.E10-07-0638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093316/
https://www.ncbi.nlm.nih.gov/pubmed/21411629
http://dx.doi.org/10.1091/mbc.E10-07-0638

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