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Cytosolic aggregates perturb the degradation of nontranslocated secretory and membrane proteins
A wide range of diseases are associated with the accumulation of cytosolic protein aggregates. The effects of these aggregates on various aspects of normal cellular protein homeostasis remain to be determined. Here we find that cytosolic aggregates, without necessarily disrupting proteasome function...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093316/ https://www.ncbi.nlm.nih.gov/pubmed/21411629 http://dx.doi.org/10.1091/mbc.E10-07-0638 |