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An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

 Epithelial-mesenchymal transition (EMT) is a form of cellular plasticity that is critical for embryonic development and tumor metastasis. A double-negative feedback loop involving the miR-200 family and ZEB (zinc finger E-box-binding homeobox) transcription factors has been postulated to control th...

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Detalles Bibliográficos
Autores principales: Gregory, Philip A., Bracken, Cameron P., Smith, Eric, Bert, Andrew G., Wright, Josephine A., Roslan, Suraya, Morris, Melanie, Wyatt, Leila, Farshid, Gelareh, Lim, Yat-Yuen, Lindeman, Geoffrey J., Shannon, M. Frances, Drew, Paul A., Khew-Goodall, Yeesim, Goodall, Gregory J.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093321/
https://www.ncbi.nlm.nih.gov/pubmed/21411626
http://dx.doi.org/10.1091/mbc.E11-02-0103