Cargando…
Exophilin8 transiently clusters insulin granules at the actin-rich cell cortex prior to exocytosis
Exophilin8/MyRIP/Slac2-c is an effector protein of the small GTPase Rab27a and is specifically localized on retinal melanosomes and secretory granules. We investigated the role of exophilin8 in insulin granule trafficking. Exogenous expression of exophilin8 in pancreatic β cells or their cell line,...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093323/ https://www.ncbi.nlm.nih.gov/pubmed/21441305 http://dx.doi.org/10.1091/mbc.E10-05-0404 |