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The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation

DNA replication in Saccharomyces cerevisiae proceeds according to a temporal program. We have investigated the role of the telomere-binding Ku complex in specifying late replication of telomere-proximal sequences. Genome-wide analysis shows that regions extending up to 80 kb from telomeres replicate...

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Detalles Bibliográficos
Autores principales: Lian, Hui-Yong, Robertson, E. Douglas, Hiraga, Shin-ichiro, Alvino, Gina M., Collingwood, David, McCune, Heather J., Sridhar, Akila, Brewer, Bonita J., Raghuraman, M. K., Donaldson, Anne D.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093326/
https://www.ncbi.nlm.nih.gov/pubmed/21441303
http://dx.doi.org/10.1091/mbc.E10-06-0549