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Overexpression of peroxisomal testis-specific 1 protein induces germ cell apoptosis and leads to infertility in male mice
Peroxisomal testis-specific 1 gene (Pxt1) is the only male germ cell–specific gene that encodes a peroxisomal protein known to date. To elucidate the role of Pxt1 in spermatogenesis, we generated transgenic mice expressing a c-MYC-PXT1 fusion protein under the control of the PGK2 promoter. Overexpr...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093327/ https://www.ncbi.nlm.nih.gov/pubmed/21460186 http://dx.doi.org/10.1091/mbc.E09-12-0993 |