Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain

Forkhead transcription factors (FOXOs) alter a diverse array of cellular processes including the cell cycle, oxidative stress resistance, and aging. Insulin/Akt activation directs phosphorylation and cytoplasmic sequestration of FOXO away from its target genes and serves as an endpoint of a complex...

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Detalles Bibliográficos
Autores principales: Senapedis, William T., Kennedy, Caleb J., Boyle, Patrick M., Silver, Pamela A.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093329/
https://www.ncbi.nlm.nih.gov/pubmed/21460183
http://dx.doi.org/10.1091/mbc.E10-10-0854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093329/
https://www.ncbi.nlm.nih.gov/pubmed/21460183
http://dx.doi.org/10.1091/mbc.E10-10-0854

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