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Transcriptional Regulation: Effects of Promoter Proximal Pausing on Speed, Synchrony and Reliability

Recent whole genome polymerase binding assays in the Drosophila embryo have shown that a substantial proportion of uninduced genes have pre-assembled RNA polymerase-II transcription initiation complex (PIC) bound to their promoters. These constitute a subset of promoter proximally paused genes for w...

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Detalles Bibliográficos
Autores principales: Boettiger, Alistair N., Ralph, Peter L., Evans, Steven N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093350/
https://www.ncbi.nlm.nih.gov/pubmed/21589887
http://dx.doi.org/10.1371/journal.pcbi.1001136