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Transcriptional Regulation: Effects of Promoter Proximal Pausing on Speed, Synchrony and Reliability
Recent whole genome polymerase binding assays in the Drosophila embryo have shown that a substantial proportion of uninduced genes have pre-assembled RNA polymerase-II transcription initiation complex (PIC) bound to their promoters. These constitute a subset of promoter proximally paused genes for w...
Autores principales: | Boettiger, Alistair N., Ralph, Peter L., Evans, Steven N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093350/ https://www.ncbi.nlm.nih.gov/pubmed/21589887 http://dx.doi.org/10.1371/journal.pcbi.1001136 |
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