Quantitative Epistasis Analysis and Pathway Inference from Genetic Interaction Data

Inferring regulatory and metabolic network models from quantitative genetic interaction data remains a major challenge in systems biology. Here, we present a novel quantitative model for interpreting epistasis within pathways responding to an external signal. The model provides the basis of an exper...

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Detalles Bibliográficos
Autores principales: Phenix, Hilary, Morin, Katy, Batenchuk, Cory, Parker, Jacob, Abedi, Vida, Yang, Liu, Tepliakova, Lioudmila, Perkins, Theodore J., Kærn, Mads
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093353/
https://www.ncbi.nlm.nih.gov/pubmed/21589890
http://dx.doi.org/10.1371/journal.pcbi.1002048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093353/
https://www.ncbi.nlm.nih.gov/pubmed/21589890
http://dx.doi.org/10.1371/journal.pcbi.1002048

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