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An E2F1-Mediated DNA Damage Response Contributes to the Replication of Human Cytomegalovirus

DNA damage resulting from intrinsic or extrinsic sources activates DNA damage responses (DDRs) centered on protein kinase signaling cascades. The usual consequences of inducing DDRs include the activation of cell cycle checkpoints together with repair of the damaged DNA or induction of apoptosis. Ma...

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Detalles Bibliográficos
Autores principales: E, Xiaofei, Pickering, Mary T., Debatis, Michelle, Castillo, Jonathan, Lagadinos, Alexander, Wang, Shixia, Lu, Shan, Kowalik, Timothy F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093362/
https://www.ncbi.nlm.nih.gov/pubmed/21589897
http://dx.doi.org/10.1371/journal.ppat.1001342