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Helicobacter pylori Perturbs Iron Trafficking in the Epithelium to Grow on the Cell Surface

Helicobacter pylori (Hp) injects the CagA effector protein into host epithelial cells and induces growth factor-like signaling, perturbs cell-cell junctions, and alters host cell polarity. This enables Hp to grow as microcolonies adhered to the host cell surface even in conditions that do not suppor...

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Detalles Bibliográficos
Autores principales: Tan, Shumin, Noto, Jennifer M., Romero-Gallo, Judith, Peek, Richard M., Amieva, Manuel R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093365/
https://www.ncbi.nlm.nih.gov/pubmed/21589900
http://dx.doi.org/10.1371/journal.ppat.1002050