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Hypoxia and Prostaglandin E Receptor 4 Signalling Pathways Synergise to Promote Endometrial Adenocarcinoma Cell Proliferation and Tumour Growth

The prostaglandin endoperoxide synthase (PTGS) pathway is a potent driver of tumour development in humans by enhancing the biosynthesis and signalling of prostaglandin (PG) E(2). PTGS2 expression and PGE(2) biosynthesis is elevated in endometrial adenocarcinoma, however the mechanism whereby PTGS an...

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Detalles Bibliográficos
Autores principales: Catalano, Rob D., Wilson, Martin R., Boddy, Sheila C., McKinlay, Andrew T. M., Sales, Kurt J., Jabbour, Henry N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093383/
https://www.ncbi.nlm.nih.gov/pubmed/21589857
http://dx.doi.org/10.1371/journal.pone.0019209