Cargando…

Hypoxia and Prostaglandin E Receptor 4 Signalling Pathways Synergise to Promote Endometrial Adenocarcinoma Cell Proliferation and Tumour Growth

The prostaglandin endoperoxide synthase (PTGS) pathway is a potent driver of tumour development in humans by enhancing the biosynthesis and signalling of prostaglandin (PG) E(2). PTGS2 expression and PGE(2) biosynthesis is elevated in endometrial adenocarcinoma, however the mechanism whereby PTGS an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Catalano, Rob D., Wilson, Martin R., Boddy, Sheila C., McKinlay, Andrew T. M., Sales, Kurt J., Jabbour, Henry N.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093383/ https://www.ncbi.nlm.nih.gov/pubmed/21589857 http://dx.doi.org/10.1371/journal.pone.0019209

Ejemplares similares

Prostaglandin F(2α)-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium–calcineurin–NFAT pathway
por: Sales, Kurt J., et al.
Publicado: (2009)

Seminal Plasma Enhances Cervical Adenocarcinoma Cell Proliferation and Tumour Growth In Vivo
por: Sutherland, Jason R., et al.
Publicado: (2012)

Novel Roles for Hypoxia and Prostaglandin E(2) in the Regulation of IL-8 During Endometrial Repair
por: Maybin, Jacqueline A., et al.
Publicado: (2011)

Synergise or perish
por: Grover, Harpreet Singh
Publicado: (2021)

The Regulation of Vascular Endothelial Growth Factor by Hypoxia and Prostaglandin F(2α) during Human Endometrial Repair
por: Maybin, Jacqueline A., et al.
Publicado: (2011)

Comprehensive expression analysis of prostanoid enzymes and receptors in the human endometrium across the menstrual cycle
por: Catalano, Rob D., et al.
Publicado: (2011)

Prokineticin 1 induces Dickkopf 1 expression and regulates cell proliferation and decidualization in the human endometrium
por: Macdonald, Linsay J., et al.
Publicado: (2011)

F-Prostaglandin receptor regulates endothelial cell function via fibroblast growth factor-2
por: Keightley, Margaret C, et al.
Publicado: (2010)

Prostaglandin E(2) and F(2α) activate the FP receptor and up-regulate cyclooxygenase-2 expression via the cyclic AMP response element
por: Sales, Kurt J., et al.
Publicado: (2008)

MYCN and mutationally activated ALK synergise in neuroblastoma
Publicado: (2012)

Chorionic gonadotrophin regulates CXCR4 expression in human endometrium via E-series prostanoid receptor 2 signalling to PI3K–ERK1/2: implications for fetal–maternal crosstalk for embryo implantation
por: Sales, Kurt J., et al.
Publicado: (2011)

Interleukin 1 beta synergises with interleukin 2 in the outgrowth of autologous tumour-reactive CD8+ effectors.
por: Baxevanis, C. N., et al.
Publicado: (1994)

Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase
por: Di Gennaro, E, et al.
Publicado: (2010)

A role for lipoxin A(4) as an anti-inflammatory mediator in the human endometrium
por: Macdonald, Linsay J, et al.
Publicado: (2011)

Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division
por: Maia, Ana Rita R., et al.
Publicado: (2018)

A nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity
por: Li, Xia, et al.
Publicado: (2020)

EEF2K silencing inhibits tumour progression through repressing SPP1 and synergises with BET inhibitors in melanoma
por: Deng, Guangtong, et al.
Publicado: (2022)

PGF(2α)-F-prostanoid receptor signalling via ADAMTS1 modulates epithelial cell invasion and endothelial cell function in endometrial cancer
por: Keightley, Margaret C, et al.
Publicado: (2010)

Prokineticin 1 mediates fetal-maternal dialogue regulating endometrial leukemia inhibitory factor
por: Evans, Jemma, et al.
Publicado: (2009)

Expression of oestrogen receptors, ERα, ERβ, and ERβ variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERα
por: Collins, Frances, et al.
Publicado: (2009)

Synergisic effect of APRIL knockdown and Jiedu Xiaozheng Yin, a Chinese medicinal recipe, on the inhibition of hepatocellular carcinoma cell proliferation
por: Liu, Zhizhen, et al.
Publicado: (2017)

A small molecule inhibitor of XIAP induces apoptosis and synergises with vinorelbine and cisplatin in NSCLC
por: Dean, E J, et al.
Publicado: (2010)

A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy
por: Sulaiman, Rania S., et al.
Publicado: (2016)

Acute effect of low-dose thiacloprid exposure synergised by tebuconazole in a parasitoid wasp
por: Willow, Jonathan, et al.
Publicado: (2019)

Tobramycin and bicarbonate synergise to kill planktonic Pseudomonas aeruginosa, but antagonise to promote biofilm survival
por: Kaushik, Karishma S, et al.
Publicado: (2016)

Recursive integration of synergised graph representations of multi-omics data for cancer subtypes identification
por: Madhumita, et al.
Publicado: (2022)

Potential of damage associated molecular patterns in synergising radiation and the immune response in oesophageal cancer
por: Donlon, Noel E, et al.
Publicado: (2023)

Prostaglandin receptor EP3 regulates cell proliferation and migration with impact on survival of endometrial cancer patients
por: Zhu, Junyan, et al.
Publicado: (2017)

Endometrial Adenocarcinoma and Extragenital Tumours in Guinea-pigs with “Ovarian Fragmentation”
por: Bruzzone, S., et al.
Publicado: (1954)

The Art of People Management in Libraries
por: McKinlay, James
Publicado: (2010)

Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin
por: Sivalingam, Vanitha N., et al.
Publicado: (2019)

α-Tocopheryl succinate and TRAIL selectively synergise in induction of apoptosis in human malignant mesothelioma cells
por: Tomasetti, M, et al.
Publicado: (2004)

TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells
por: Tuthill, Mark H, et al.
Publicado: (2014)

Synergising Public Health Concepts with the Sendai Framework for Disaster Risk Reduction: A Conceptual Glossary
por: Phibbs, Suzanne, et al.
Publicado: (2016)

Dasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1
por: Xu, Li, et al.
Publicado: (2017)

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress
por: Wallington-Beddoe, Craig T., et al.
Publicado: (2017)

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models
por: Mieszczanek, Juliusz, et al.
Publicado: (2019)

Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment
por: Rushworth, Linda K., et al.
Publicado: (2019)

Synergising single-cell resolution and 4sU labelling boosts inference of transcriptional bursting
por: Edwards, David M., et al.
Publicado: (2023)

IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis
por: Perimenis, Philippos, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5p7j81ng63kfkjqk2tas15c7v7