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PAX6 Haplotypes Are Associated with High Myopia in Han Chinese

BACKGROUND: The paired box 6 (PAX6) gene is considered as a master gene for eye development. Linkage of myopia to the PAX6 region on chromosome 11p13 was shown in several studies, but the results for association between myopia and PAX6 were inconsistent so far. METHODOLOGY/PRINCIPAL FINDINGS: We gen...

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Detalles Bibliográficos
Autores principales: Jiang, Bo, Yap, Maurice K. H., Leung, Kim Hung, Ng, Po Wah, Fung, Wai Yan, Lam, Wai Wa, Gu, Yang-shun, Yip, Shea Ping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093386/
https://www.ncbi.nlm.nih.gov/pubmed/21589860
http://dx.doi.org/10.1371/journal.pone.0019587