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Transient Gastric Irritation in the Neonatal Rats Leads to Changes in Hypothalamic CRF Expression, Depression- and Anxiety-Like Behavior as Adults

AIMS: A disturbance of the brain-gut axis is a prominent feature in functional bowel disorders (such as irritable bowel syndrome and functional dyspepsia) and psychological abnormalities are often implicated in their pathogenesis. We hypothesized that psychological morbidity in these conditions may...

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Detalles Bibliográficos
Autores principales: Liu, Liansheng, Li, Qian, Sapolsky, Robert, Liao, Min, Mehta, Kshama, Bhargava, Aditi, Pasricha, Pankaj J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093391/
https://www.ncbi.nlm.nih.gov/pubmed/21589865
http://dx.doi.org/10.1371/journal.pone.0019498