Contribution of Cytochrome P450 and ABCB1 Genetic Variability on Methadone Pharmacokinetics, Dose Requirements, and Response

Although the efficacy of methadone maintenance treatment (MMT) in opioid dependence disorder has been well established, the influence of methadone pharmacokinetics in dose requirement and clinical outcome remains controversial. The aim of this study is to analyze methadone dosage in responder and no...

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Detalles Bibliográficos
Autores principales: Fonseca, Francina, de la Torre, Rafael, Díaz, Laura, Pastor, Antonio, Cuyàs, Elisabet, Pizarro, Nieves, Khymenets, Olha, Farré, Magí, Torrens, Marta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093392/
https://www.ncbi.nlm.nih.gov/pubmed/21589866
http://dx.doi.org/10.1371/journal.pone.0019527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093392/
https://www.ncbi.nlm.nih.gov/pubmed/21589866
http://dx.doi.org/10.1371/journal.pone.0019527

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