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Construction of a novel expression cassette for increasing transgene expression in vivo in endothelial cells of large blood vessels
The success of gene therapy hinges on achievement of adequate transgene expression. To ensure high transgene expression, many gene-therapy vectors include highly active virus-derived transcriptional elements. Other vectors include tissue-specific eukaryotic transcriptional elements, intended to limi...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093449/ https://www.ncbi.nlm.nih.gov/pubmed/21179172 http://dx.doi.org/10.1038/gt.2010.173 |