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Structure of Rhomboid Protease in a Lipid Environment

Structures of the prokaryotic homologue of rhomboid proteases reveal a core of six transmembrane helices, with the active-site residues residing in a hydrophilic cavity. The native environment of rhomboid protease is a lipid bilayer, yet all the structures determined thus far are in a nonnative dete...

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Detalles Bibliográficos
Autor principal: Vinothkumar, Kutti R.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093617/
https://www.ncbi.nlm.nih.gov/pubmed/21256137
http://dx.doi.org/10.1016/j.jmb.2011.01.029