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In vitro controlled release of colon targeted mesalamine from compritol ATO 888 based matrix tablets using factorial design

A controlled release matrix formulation for mesalamine was designed and developed to achieve a 24 h release profile. Using compritol 888 ATO (glyceryl behenate) as an inert matrix-forming agent to control the release of mesalamine, formulation granules containing the solid dispersions were investiga...

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Detalles Bibliográficos
Autores principales: Patel, J.K., Patel, N.V., Shah, S.H.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093632/
https://www.ncbi.nlm.nih.gov/pubmed/21589801