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In vitro controlled release of colon targeted mesalamine from compritol ATO 888 based matrix tablets using factorial design
A controlled release matrix formulation for mesalamine was designed and developed to achieve a 24 h release profile. Using compritol 888 ATO (glyceryl behenate) as an inert matrix-forming agent to control the release of mesalamine, formulation granules containing the solid dispersions were investiga...
| Autores principales: | , , |
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| 格式: | Texto |
| 語言: | English |
| 出版: |
Medknow Publications
2009
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| 主題: | |
| 在線閱讀: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093632/ https://www.ncbi.nlm.nih.gov/pubmed/21589801 |