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Probing Carbohydrate Product Expulsion from a Processive Cellulase with Multiple Absolute Binding Free Energy Methods
Understanding the enzymatic mechanism that cellulases employ to degrade cellulose is critical to efforts to efficiently utilize plant biomass as a sustainable energy resource. A key component of cellulase action on cellulose is product inhibition from monosaccharide and disaccharides in the product...
Autores principales: | Bu, Lintao, Beckham, Gregg T., Shirts, Michael R., Nimlos, Mark R., Adney, William S., Himmel, Michael E., Crowley, Michael F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093888/ https://www.ncbi.nlm.nih.gov/pubmed/21454590 http://dx.doi.org/10.1074/jbc.M110.212076 |
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