Cargando…

Architecture of the RNA polymerase–Spt4/5 complex and basis of universal transcription processivity

Related RNA polymerases (RNAPs) carry out cellular gene transcription in all three kingdoms of life. The universal conservation of the transcription machinery extends to a single RNAP-associated factor, Spt5 (or NusG in bacteria), which renders RNAP processive and may have arisen early to permit evo...

Descripción completa

Detalles Bibliográficos
Autores principales: Martinez-Rucobo, Fuensanta W, Sainsbury, Sarah, Cheung, Alan CM, Cramer, Patrick
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094117/
https://www.ncbi.nlm.nih.gov/pubmed/21386817
http://dx.doi.org/10.1038/emboj.2011.64