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Analysis of effects of tRNA:message stability on frameshift frequency at the Escherichia coli RF2 programmed frameshift site.

The codon that is in-frame prior to +1 frameshifting at the E.coli prfB (RF2 gene) frameshift site is randomized to create thirty-two variants. These alleles vary 1000-fold in frameshift-dependent expression in fusions to lacZ. Frameshifting is more frequent at sites where the in-frame codon ends in...

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Detalles Bibliográficos
Autor principal: Curran, J F
Formato: Texto
Lenguaje:English
Publicado: 1993
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC309422/
https://www.ncbi.nlm.nih.gov/pubmed/8493101