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15 kDa Granulysin versus GM-CSF for monocytes differentiation: analogies and differences at the transcriptome level

BACKGROUND: Granulysin is an antimicrobial and proinflammatory protein with several isoforms. While the 9 kDa isoform is a well described cytolytic molecule with pro-inflammatory activity, the functions of the 15 kDa isoform is less well understood. Recently it was shown that 15 kDa Granulysin can a...

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Detalles Bibliográficos
Autores principales: Castiello, Luciano, Stroncek, David F, Finn, Michael W, Wang, Ena, Marincola, Francesco M, Clayberger, Carol, Krensky, Alan M, Sabatino, Marianna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094223/
https://www.ncbi.nlm.nih.gov/pubmed/21501511
http://dx.doi.org/10.1186/1479-5876-9-41