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Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres

BACKGROUND: Breast cancer is one of the most prevalent cancers in the world and more than one million women are diagnosed leading to 410,000 deaths every year. In our previous studies new chalcone-imidazolone conjugates were prepared and evaluated for their anticancer activity in a panel of 53 human...

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Detalles Bibliográficos
Autores principales: Ramaiah, M Janaki, Pushpavalli, SNCVL, Krishna, G Rama, Sarma, Pranjal, Mukhopadhyay, Debasmita, Kamal, Ahmed, Bhadra, Utpal, Bhadra, Manika Pal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094261/
https://www.ncbi.nlm.nih.gov/pubmed/21518433
http://dx.doi.org/10.1186/1475-2867-11-11