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Association of TRB3 Q84R polymorphism with polycystic ovary syndrome in Chinese women

BACKGROUND: Tribbles 3 (TRB3) affects insulin signalling by inhibiting insulin-stimulated Akt phosphorylation and subsequent activation. A single nucleotide polymorphism located in the second extron of the human TRB3 gene is thought to be associated with insulin resistance. The latter is a core abno...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Fu, Li, Zhang, Qiufang, Yan, Liying, Ma, Yanmin, Tu, Binbin, Liu, Nana, Qiao, Jie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094280/
https://www.ncbi.nlm.nih.gov/pubmed/21492415
http://dx.doi.org/10.1186/1477-7827-9-46